Over-the-Counter (OTC) drugs for fibromyalgia insomnia are those that can be purchased from a pharmacy without a prescription. These drugs include Nytol, Sleep-Eze, Sominex and others.  Most of these products contain antihistamines, such as diphenhydramine (Benadryl), that act as sedatives.

Patients suffering from fibromyalgia insomnia who use OTC drugs may not always experience relief from their symptoms, and may experience adverse effects.  Some antihistamines produce effects such as a dry mouth, dry eyes, urinary retention, confusion and even delirium. Some users complain of vivid dreams and next day hangover effects when using an OTC drug for  insomnia.  It is important to check the label of ingredients on over-the-counter (OTC) treatment formulas, including those sleep aids designated as "nighttime" or "P.M." formulas, to see if they contain antihistamines.  A common OTC antihistamine is diphenhydramine hydrochloride.